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Year : 2021  |  Volume : 23  |  Issue : 1  |  Page : 16-23

Techno-innovations and molecular methods for diagnosis of COVID-19: Updates from India


1 Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
2 Division of Innovation and Translational Research, Indian Council of Medical Research, New Delhi, India
3 Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India
4 National Institute of Nursing Education, Postgraduate Institute of Medical Education and Research, Chandigarh, India
5 Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
6 Department of Biochemistry, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
7 Advance Pediatric Centre, Hematology Oncology Unit, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Dr Jitender Gairolla
Senior Resident, Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jmms.jmms_195_20

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The rapid diagnosis of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection relies on the availability of a robust method. The demand for SARS-CoV-2 diagnostic kits and other desirable consumables for timely diagnosis have increased drastically after the current pandemic. The cumulative efforts by scientists, funding agencies, regulatory authorities, and corporates have accelerated the process of kit development. Worldwide, rapid molecular techno progression to characterize the biology of any pathogen witnessed during this pandemic faster than ever. Moreover, a paradigm shift from real-time polymerase chain reaction technique to highly sensitive novel CRISPR technology has been observed. India, second most populous country actively leveraged molecular technologies for rapid diagnosis of SARS-CoV-2. This paper focuses on paradigm shift in the methods for diagnosis of SARS-CoV-2 infection with a focus on molecular innovations carried out in India indigenously.


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